While the prevailing style of architecture was trabeate, employing pillars, beams and lintels, this brought in the arcuate style of construction, with its arches and beams, which flourished under Mughal patronage and by incorporating elements of Indian architecture, especially Rajasthani architecture including decorative corbel brackets, balconies, pendentive decorations and indeed kiosks or chhatris, to develop a distinct Mughal architecture style, which was to become a lasting legacy of the Mughal rule. 

The combination of red sandstone and white marble was previously seen in Delhi Sultanate period tombs and mosques. 

The tomb built of rubble masonry and red sandstone, uses white marble as a cladding material and also for the flooring, lattice screens (jaalis), door frames, eaves (chhajja) and for the main dome. 

The symmetrical and simple designed on the exterior is in sharp contrast with the complex interior floor plan, of inner chambers, which is a square 'ninefold plan', where eight two-storied vaulted chambers radiate from the central, double-height domed chamber.  

As a contrast to the pure white exterior dome, rest of the building is made up of red sandstone, with white and black marble and yellow sandstone detailing, to relieve the monotony. 

The highly geometrical and enclosed Paradise garden is divided into four squares by paved walkways (khiyabans) and two bisecting central water channels, reflecting the four rivers that flow in jannat, the Islamic concept of paradise. 

Underneath this white dome in a domed chamber (hujra), lies the central octagonal sepulcher, the burial chamber containing a single cenotaph, that of the second Mughal Emperor, Humayun aligned on the north–south axis, as per Islamic tradition, wherein the head is placed to the north, while the face is turned sideways towards Mecca.  

The double or 'double-layered' dome, has its outer layer which supports the white marble exterior, while the inner part gives shape to the cavernous interior volume. 

The tomb can be entered through an imposing entrance iwan (high arc) on the south, which is slightly recessed, while others sides are covered with intricate jaalis, stone latticework